Hepatitis C virus: virology and life cycle

  title={Hepatitis C virus: virology and life cycle},
  author={Chang Wook Kim and K M Chang},
  booktitle={Clinical and molecular hepatology},
Hepatitis C virus (HCV) is a positive sense, single-stranded RNA virus in the Flaviviridae family. It causes acute hepatitis with a high propensity for chronic infection. Chronic HCV infection can progress to severe liver disease including cirrhosis and hepatocellular carcinoma. In the last decade, our basic understanding of HCV virology and life cycle has advanced greatly with the development of HCV cell culture and replication systems. Our ability to treat HCV infection has also been improved… CONTINUE READING


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