Hepatitis C virus, cryoglobulinaemia, and vasculitis: immune complex relations.

@article{Sansonno2005HepatitisCV,
  title={Hepatitis C virus, cryoglobulinaemia, and vasculitis: immune complex relations.},
  author={Domenico Sansonno and Franco Dammacco},
  journal={The Lancet. Infectious diseases},
  year={2005},
  volume={5 4},
  pages={
          227-36
        }
}
Several viruses are involved in the development of systemic vasculitides. Hepatitis C virus (HCV) has been shown to be closely related to mixed cryoglobulinaemia, an immune complex-mediated vasculitis. HCV particles and non-enveloped nucleocapsid protein participate in the formation of immune complexes. Once formed, immune complexes precipitate in many organs, including the skin, kidneys, and peripheral nerve fibres. Viral proteins confer peculiar physical and chemical properties on… CONTINUE READING

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