Hepatitis C recurrence after liver transplantation: Viral and histologic response to full-dose PEG-interferon and ribavirin.

@article{Otn2006HepatitisCR,
  title={Hepatitis C recurrence after liver transplantation: Viral and histologic response to full-dose PEG-interferon and ribavirin.},
  author={Elena Mac{\'i}as Ot{\'o}n and Rafael B{\'a}rcena and Jos{\'e} Mar{\'i}a Moreno-Planas and Valentin Cuervas-Mons and Ana Moreno-Zamora and Cristobol Barrios and Silvia Garc{\'i}a-Garz{\'o}n and Aitor Moreno and E Boullosa-Gra{\~n}a and Eduardo Rubio-Gonz{\'a}lez and M. Garc{\'i}a-Gonzalez and Carmen Carreras Blesa and Mar{\'i}a Luisa Mateos},
  journal={American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons},
  year={2006},
  volume={6 10},
  pages={
          2348-55
        }
}
Hepatitis C recurrence after liver transplantation (LT) is universal, and frequently leads to cirrhosis and death. The aim of our study was to assess the efficacy and safety of 48-weeks of full-dose peg-interferon-alpha-2a (n = 4) or alpha-2b (n = 51) plus ribavirin (>11 mg/kg/day) in a multicentric cohort of 55 patients > or =12 months after LT. All subjects had histologically proven HCV recurrence, excluding severe cholestatic recurrence. Mean age was 54.3 +/- 9.7, 77% male, 90.9% genotype 1… CONTINUE READING

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