Hepatitis C infection by polymerase chain reaction in alcoholics: false-positive ELISA results and the influence of infection on a clinical prognostic score.

@article{Caldwell1993HepatitisCI,
  title={Hepatitis C infection by polymerase chain reaction in alcoholics: false-positive ELISA results and the influence of infection on a clinical prognostic score.},
  author={Steven H Caldwell and Xing-wang Li and R M Rourk and Adam Millar and K M Sosnowski and Michael W Sue and A Sidney Barritt and R. W. McCallum and Eugene R Schiff},
  journal={The American journal of gastroenterology},
  year={1993},
  volume={88 7},
  pages={1016-21}
}
Antibody to hepatitis C as measured by the ELISA method is common in alcoholics. The presence of antibody to C 100-3 has been associated with more advanced disease. However, few studies have investigated the clinical significance of hepatitis C infection as defined by the presence of circulating viral RNA in alcoholics. We have prospectively examined 48 consecutive alcoholic patients for the presence of antibody to hepatitis C by an ELISA for antibody to the C100-3 antigen and by the reverse… CONTINUE READING