Hepatitis C Virus Infection Downregulates the Ligands of the Activating Receptor NKG2D

@article{Wen2008HepatitisCV,
  title={Hepatitis C Virus Infection Downregulates the Ligands of the Activating Receptor NKG2D},
  author={Chaoyang Wen and Xiang He and Hongfang Ma and Ningbo Hou and Congwen Wei and Ting Song and Yanhong Zhang and Liping Sun and Qingjun Ma and Hui Zhong},
  journal={Cellular and Molecular Immunology},
  year={2008},
  volume={5},
  pages={475-478}
}
Natural killer (NK) cells are a major component of the host innate immune defense against various pathogens. Several viruses, including hepatitis C virus (HCV), have developed strategies to evade the NK-cell response. In our study, we found HCV infection could trigger DNA damage response by both ataxia telangiectasia mutated (ATM) and ATM- and Rad3-related… CONTINUE READING