Hepatitis B virus translocates across a trophoblastic barrier.

  title={Hepatitis B virus translocates across a trophoblastic barrier.},
  author={Purnima Bhat and David A. Anderson},
  journal={Journal of virology},
  volume={81 13},
Mother-infant transmission of hepatitis B virus (HBV) accounts for up to 30% of worldwide chronic infections. The mechanism and high-risk period of HBV transmission from mother to infant are unknown. Although largely prevented by neonatal vaccination, significant transmission continues to occur in high-risk populations. It is unclear whether HBV can traverse an intact epithelial barrier to infect a new host. Transplacental transmission of a number of viruses relies on transcytotic pathways… CONTINUE READING


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