Hepatitis B virus quasispecies in hepatic and extrahepatic viral reservoirs in liver transplant recipients on prophylactic therapy

@article{Coffin2011HepatitisBV,
  title={Hepatitis B virus quasispecies in hepatic and extrahepatic viral reservoirs in liver transplant recipients on prophylactic therapy},
  author={C. Coffin and P. M. Mulrooney-Cousins and G. van Marle and J. Roberts and T. Michalak and N. Terrault},
  journal={Liver Transplantation},
  year={2011},
  volume={17}
}
  • C. Coffin, P. M. Mulrooney-Cousins, +3 authors N. Terrault
  • Published 2011
  • Medicine
  • Liver Transplantation
  • The characterization of hepatitis B virus (HBV) quasispecies in different compartments in liver transplant (LT) recipients may be helpful in optimizing prophylaxis regimens. The aims of this study were to evaluate liver, peripheral blood mononuclear cells (PBMC), and plasma samples for HBV and to compare the quasispecies in hepatic and extrahepatic sites in LT recipients on long‐term prophylaxis. For 12 patients followed for up to 15 years post‐LT, liver, plasma, and PBMC samples [all HBV DNA… CONTINUE READING
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