Hepatitis B virus precore/core variation and interferon therapy.

  title={Hepatitis B virus precore/core variation and interferon therapy.},
  author={Giovanna Fattovich and G. Mcintyre and Mark Thursz and K L Colman and Giovanni Giuliano and Alfredo Alberti and Howard Thomas and William F. Carman},
  volume={22 5},
Precore/core genes from hepatitis B e antigen (HBeAg)-positive and antibody to HBeAg (anti-HBe) positive individuals with active hepatitis have been analyzed to search for correlations with response to interferon before and after treatment. Pretreatment, no precore stop codon mutants were detected, even at the 3% level, in HBeAg-positive responders or nonresponders. In anti-HBe-positive patients, precore mutants did not influence response. No significant core amino acid variability was observed… CONTINUE READING


Publications citing this paper.
Showing 1-9 of 9 extracted citations

Medical Treatment of Hepatocellular Carcinoma

Mediterranean journal of hematology and infectious diseases • 2009

Prevalence of HBV genotypes in South American immigrants affected by HBV-related chronic active hepatitis.

The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases • 2007
View 1 Excerpt

Similar Papers

Loading similar papers…