Hepatitis B virus infection in chimpanzees: titration of subtypes.

  title={Hepatitis B virus infection in chimpanzees: titration of subtypes.},
  author={Lewellys F. Barker and James E. Maynard and Robert H. Purcell and Jay H. Hoofnagle and K R Berquist and William T London and Robert J Gerety and D H Krushak},
  journal={The Journal of infectious diseases},
  volume={132 4},
Thirty-four chimpanzees were inoculated with sera containing the adw, ayw, adr, or ayr subtype of hepatitis B surface antigen (HBs Ag). Twenty-nine of the animals became infected with hepatitis B virus, and in every instance the subtype of HBs Ag in the infected animal was the same as the subtype in the inoculum. Infectivity titers were established for the adw and ayw inocula. The patterns of serologic events varied in the infected animals but included most of the typical patterns of serologic… CONTINUE READING


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