Hepatitis B virus gene mutations and hepatocarcinogenesis.

  title={Hepatitis B virus gene mutations and hepatocarcinogenesis.},
  author={T Liang and En-Qiang Chen and Hong Tang},
  journal={Asian Pacific journal of cancer prevention : APJCP},
  volume={14 8},
Chronic hepatitis B virus (HBV) infection has long been the most common cause of hepatocellular carcinoma (HCC). However, some aspects of the pathogenesis of HBV infection and genesis of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) are still inconclusive. An increasing number of published studies indicate that hepatitis B virus mutations are associated with risk of HCC. These variations include, in particular, mutations in ORF S,C,X gene regions. This mini-review summarizes… CONTINUE READING


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