Hepatitis B virus escape mutants induced by antiviral therapy.


The hepatitis B virus (HBV) polymerase and envelope genes overlap in such a way that resistance mutations to antiviral agents in the reverse transcriptase gene may affect the antigenicity of the HBV surface antigen. Mutant viruses may escape serological diagnosis using specific anti-HBV surface antigen antibodies, causing occult forms of chronic hepatitis B… (More)
DOI: 10.1093/jac/dkn014


Cite this paper

@article{Sheldon2008HepatitisBV, title={Hepatitis B virus escape mutants induced by antiviral therapy.}, author={Julie A Sheldon and Vincent Soriano}, journal={The Journal of antimicrobial chemotherapy}, year={2008}, volume={61 4}, pages={766-8} }