Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures

@article{Lavanchy2004HepatitisBV,
  title={Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures},
  author={Daniel Lavanchy},
  journal={Journal of Viral Hepatitis},
  year={2004},
  volume={11}
}
  • Daniel Lavanchy
  • Published 2004
  • Medicine
  • Journal of Viral Hepatitis
  • Summary.  Hepatitis B virus (HBV) infection is a serious global health problem, with 2 billion people infected worldwide, and 350 million suffering from chronic HBV infection. The 10th leading cause of death worldwide, HBV infections result in 500 000 to 1.2 million deaths per year caused by chronic hepatitis, cirrhosis, and hepatocellular carcinoma; the last accounts for 320 000 deaths per year [ 1, 2 ]. In Western countries, the disease is relatively rare and acquired primarily in adulthood… CONTINUE READING
    2,412 Citations

    Paper Mentions

    INTERVENTIONAL CLINICAL TRIAL
    Currently, five nucleos(t)ide analogs are approved for the treatment of chronic hepatitis B, namely lamivudine, adefovir dipivoxil, telbivudine, entecavir (ETV) and tenofovir disoproxil… Expand
    ConditionsChronic Heptitis B
    InterventionDrug
    INTERVENTIONAL CLINICAL TRIAL
    Randomized open-label substudy of daily Myrcludex B (MXB) plus pegylated interferon-alpha-2a (PEG-INF-a) in patients with hepatitis B e antigen (HBeAg) negative chronic hepatitis B virus… Expand
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    InterventionDrug
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    ConditionsChronic Hepatitis B
    InterventionDrug
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