Hepatitis-B virus endemicity: heterogeneity, catastrophic dynamics and control

@article{Medley2001HepatitisBVE,
  title={Hepatitis-B virus endemicity: heterogeneity, catastrophic dynamics and control},
  author={Graham F Medley and Nathan A. Lindop and W. John Edmunds and D. James Nokes},
  journal={Nature Medicine},
  year={2001},
  volume={7},
  pages={619-624}
}
Hepatitis-B virus infection is globally ubiquitous, but its distribution is very heterogeneous, with prevalence of serological markers in various nations ranging from less than 1% to more than 90%. We propose an explanation for this diversity using a mathematical model of hepatitis-B virus transmission dynamics that shows, for the first time, 'catastrophic' behavior using realistic epidemiological processes and parameters. Our major conclusion is that the prevalence of infection is largely… CONTINUE READING
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Prevalence of hepatitisB anticore antibody in the Republic of Ireland

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