Hepatitis B virus core protein interacts with the C-terminal region of actin-binding protein.

@article{Huang2000HepatitisBV,
  title={Hepatitis B virus core protein interacts with the C-terminal region of actin-binding protein.},
  author={Congyu Huang and Eddie T. C. Lam and Lap-hing. Ting},
  journal={Journal of biomedical science},
  year={2000},
  volume={7 2},
  pages={
          160-8
        }
}
Hepatitis B viral core protein is present in the nucleus and cytoplasm of infected hepatocytes. There is a strong correlation between the intrahepatic distribution of core protein and the viral replication state and disease activity in patients with chronic hepatitis. To understand the role of core protein in the pathogenesis of HBV, we used a yeast two-hybrid system to search for cellular proteins interacting with the carboxyl terminus of core protein, as this region is involved in a number of… CONTINUE READING
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