Hepatitis B virus core promoter sequence analysis in fulminant and chronic hepatitis B.

@article{Laskus1995HepatitisBV,
  title={Hepatitis B virus core promoter sequence analysis in fulminant and chronic hepatitis B.},
  author={Tomasz Laskus and Jorge Rakela and Michael James Nowicki and David H. Persing},
  journal={Gastroenterology},
  year={1995},
  volume={109 5},
  pages={1618-23}
}
BACKGROUND & AIMS It was recently reported that two point mutations within the hepatitis B virus (HBV) core promoter region (A to T at position 1762 and G to A at position 1764) are associated with fulminant hepatitis and lead to hepatitis B e antigen (HBeAg)-negative phenotype. The aim of this study was to correlate core promoter sequence variations with HBeAg status and clinical outcome in various forms of HBV infection. METHODS Core promoter region of HBV was amplified by polymerase chain… CONTINUE READING
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