Hepatitis B virus biology.

  title={Hepatitis B virus biology.},
  author={Christoph Seeger and William S. Mason},
  journal={Microbiology and molecular biology reviews : MMBR},
  volume={64 1},
Hepadnaviruses (hepatitis B viruses) cause transient and chronic infections of the liver. Transient infections run a course of several months, and chronic infections are often lifelong. Chronic infections can lead to liver failure with cirrhosis and hepatocellular carcinoma. The replication strategy of these viruses has been described in great detail, but virus-host interactions leading to acute and chronic disease are still poorly understood. Studies on how the virus evades the immune response… CONTINUE READING
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