Hepatitis B virus X protein in liver tumor microenvironment

@inproceedings{Fu2016HepatitisBV,
  title={Hepatitis B virus X protein in liver tumor microenvironment},
  author={Sha Fu and Rong-rong Zhou and Ning Li and Yan Huang and Xue-gong Fan},
  booktitle={Tumor Biology},
  year={2016}
}
Encoded by the hepatitis B virus, hepatitis B virus X protein (HBx) is a multifunctional, potentially oncogenic protein that acts primarily during the progression from chronic hepatitis B to cirrhosis and hepatocellular carcinoma (HCC). In recent decades, it has been established that chronic inflammation generates a tumor-supporting microenvironment. HCC is a typical chronic inflammation-related cancer, and inflammation is the main risk factor for HCC progression. The viral transactivator HBx… CONTINUE READING

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