Hepatitis B virus S mutants in liver transplant recipients who were reinfected despite hepatitis B immune globulin prophylaxis.

@article{Ghany1998HepatitisBV,
  title={Hepatitis B virus S mutants in liver transplant recipients who were reinfected despite hepatitis B immune globulin prophylaxis.},
  author={Marc G Ghany and B Ayola and Federico Guillermo Villamil and Robert Gish and Sergio Rojter and John Moore Vierling and A S Lok},
  journal={Hepatology},
  year={1998},
  volume={27 1},
  pages={213-22}
}
Long-term hepatitis B immune globulin (HBIG) has been shown to reduce hepatitis B virus (HBV) reinfection in patients transplanted for hepatitis B. The aim of this study was to determine the prevalence of HBV S gene mutations in liver transplant recipients who developed recurrent hepatitis B despite HBIG prophylaxis, and to determine if these mutations can revert after withdrawal of HBIG. The entire S gene sequences in pre- and posttransplant sera from 20 patients who developed recurrent… CONTINUE READING