Hepatitis B vaccine in pregnancy: immunogenicity, safety and transfer of antibodies to infants.

@article{Ayoola1987HepatitisBV,
  title={Hepatitis B vaccine in pregnancy: immunogenicity, safety and transfer of antibodies to infants.},
  author={Ephraim Ayobanji Ayoola and Abiodun O. Johnson},
  journal={International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics},
  year={1987},
  volume={25 4},
  pages={
          297-301
        }
}
To determine the safety and immunogenicity of hepatitis B vaccine in pregnancy, 72 pregnant Nigerians who were negative for markers of hepatitis B virus (HBV) were given two intramuscular doses of vaccine (Heptavax, Merck) in the third trimester. One month after the second dose (at T2), 84% were anti HBs positive. No significant effect was observed in the mothers or their newborns. Passive transfer of anti HBs occurred in 59% of the newborns. The antibodies disappeared rapidly in these infants… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 16 CITATIONS

CDC guidance for evaluating health-care personnel for hepatitis B virus protection and for administering postexposure management.

  • MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports
  • 2013
VIEW 1 EXCERPT
CITES BACKGROUND

Vaccination during pregnancy.

  • Canadian family physician Medecin de famille canadien
  • 2011