Hepatitis B surface antigen levels during the natural history of chronic hepatitis B: a perspective on Asia.

@article{Nguyen2010HepatitisBS,
  title={Hepatitis B surface antigen levels during the natural history of chronic hepatitis B: a perspective on Asia.},
  author={Tin A. Nguyen and Alexander J Thompson and Scott Bowden and Catherine M N Croagh and Sally S. Bell and Paul Vincent Desmond and Miriam Sklair Levy and Stephen A. Locarnini},
  journal={Journal of hepatology},
  year={2010},
  volume={52 4},
  pages={508-13}
}
BACKGROUND & AIMS Data from clinical trials suggest a potential role for on-treatment monitoring of serum HBsAg titres during interferon-alpha (pegIFN) therapy in predicting virological responses. However, baseline HBsAg titres during the natural history of chronic hepatitis B (CHB) have not been well-characterized. We aimed to define the serum HBsAg titres during the different phases of CHB in a cohort of Asian patients infected with either genotype B or C HBV. METHODS Two-hundred and twenty… CONTINUE READING
Highly Influential
This paper has highly influenced 12 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
139 Citations
25 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 139 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 25 references

Hepatitis B virus surface antigen levels : a guide to sustained response to peginterferon alfa - 2 a in HBeAg - negative chronic hepatitis B

  • R Moucari, V Mackiewicz, O Lada, MP Ripault, C Castelnau, M Martinot-Peignoux
  • Hepatology
  • 2009

Serum HBsAg concentration: Relationship to intrahepatic and serum markers of HBV replication

  • A Thompson, T Nguyen, +5 authors S. Locarnini
  • J Hepatol
  • 2009
1 Excerpt

Early reduction of serum HBsAg levels in HBeAg - negative chronic hepatitis B patients achieving sustained virological response after Peginter - feron alfa - 2 a + /  ribavirin treatment

  • V Rijckborst, MJ Borg, US Akarca, P Grima, R Flisiak, I Vafiadis-Zouboulis
  • Hepatology
  • 2008

HBsAg serum levels correlate with total liver HBV DNA but not with cccDNA

  • A Thompson, T Nguyen, +5 authors S Locarnini
  • Hepatology
  • 2008

On - treatment HBsAg decline during peginterferon alfa - 2 a ( 40 KD ) + /  lamivudine in patients with HBeAg - positive CHB as a potential predictor of durable off - treatment response

  • G Lau, P Marcellin, MR Brunetto, T Piratvisuth, H Kapprell, P Button
  • Hepatology
  • 2008

Similar Papers

Loading similar papers…