Hepatitis B Virus X Protein Sensitizes TRAIL-Induced Hepatocyte Apoptosis by Inhibiting the E3 Ubiquitin Ligase A20

@inproceedings{Zhang2015HepatitisBV,
  title={Hepatitis B Virus X Protein Sensitizes TRAIL-Induced Hepatocyte Apoptosis by Inhibiting the E3 Ubiquitin Ligase A20},
  author={Hang Zhang and Chang-xin Huang and Yanli Wang and Zhe Lu and Ningtong Zhuang and Dongjiu Zhao and Jianqin He and Liyun Shi and Dominique Delmas},
  booktitle={PloS one},
  year={2015}
}
Hepatitis B virus (HBV) infection causes hepatocyte death and liver damage, which may eventually lead to cirrhosis and liver cancer. Hepatitis B virus X protein (HBx) is a key antigen that is critically involved in HBV-associated liver diseases. However, the molecular basis for its pathogenesis, particularly in liver damage, has not been well defined. Herein, we report that HBx was able to enhance the susceptibility of hepatocytes to TNF-related apoptosis-inducing ligand (TRAIL)-induced… CONTINUE READING
Highly Cited
This paper has 17 citations. REVIEW CITATIONS
Recent Discussions
This paper has been referenced on Twitter 18 times over the past 90 days. VIEW TWEETS
10 Extracted Citations
43 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 10 extracted citations

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 43 references

Hepatitis B virus-induced hepatocellular carcinoma

  • C Xu, ZhouW, Y Wang, L Qiao
  • Cancer Lett 345: 216–222. doi: 10.1016/j.canlet…
  • 2014
1 Excerpt

Hepatitis B virus X protein-induced aberrant epigenetic modifications contributing to human hepatocellular carcinoma pathogenesis

  • Y Tian, YangW, J Song, Y Wu, B Ni
  • Mol Cell Biol
  • 2013
1 Excerpt

Similar Papers

Loading similar papers…