Hepatitis B: reflections on the current approach to antiviral therapy.

@article{Zoulim2008HepatitisBR,
  title={Hepatitis B: reflections on the current approach to antiviral therapy.},
  author={Fabien Zoulim and Robert R Perrillo},
  journal={Journal of hepatology},
  year={2008},
  volume={48 Suppl 1},
  pages={S2-19}
}
This article summarizes the current state of antiviral therapy of hepatitis B with special attention given to areas that remain controversial or poorly defined. Strict adherence to liver association practice guidelines may result in missed opportunities to treat patients with significant underlying liver disease. In particular, recommended ALT thresholds may not appropriately reflect disease activity or degree of fibrosis. There is growing evidence that an alternative treatment paradigm for… CONTINUE READING