Hepatic venocclusive disease associated with the consumption of pyrrolizidine-containing dietary supplements.

@article{Ridker1985HepaticVD,
  title={Hepatic venocclusive disease associated with the consumption of pyrrolizidine-containing dietary supplements.},
  author={Paul M. Ridker and Seitaro Ohkuma and William V. McDermott and Charles Trey and Ryan J. Huxtable},
  journal={Gastroenterology},
  year={1985},
  volume={88 4},
  pages={1050-4}
}
Venocclusive disease, a form of Budd-Chiari syndrome, was diagnosed in a 49-yr-old woman. The patient had portal hypertension associated with obliteration of the smaller hepatic venules. A liver biopsy specimen showed centrilobular necrosis and congestion. Analysis of food supplements the woman regularly consumed showed the presence of pyrrolizidine… CONTINUE READING