Hepatic tyrosine aminotransferase and glucocorticoid abuse in meat cattle.

@article{Bertarelli2012HepaticTA,
  title={Hepatic tyrosine aminotransferase and glucocorticoid abuse in meat cattle.},
  author={D. Bertarelli and Andrea Balbo and Monica Carletti and Thomas A Cannizzo and Flavia Girolami and C Nebbia},
  journal={Journal of veterinary pharmacology and therapeutics},
  year={2012},
  volume={35 6},
  pages={
          596-603
        }
}
Besides being extensively applied as therapeutical remedies, glucocorticoids (GCs) - most notably dexamethasone or prednisolone - are also illegally used in livestock for growth-promoting purposes. This study was designed to assess the suitability of liver tyrosine aminotransferase (TAT), a gluconeogenic enzyme known to be induced by GCs, to act as a reliable candidate biomarker to screen for GC abuse in cattle. Enzyme activity was measured spectrophotometrically in liver cytosols or in cell… CONTINUE READING
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