Hepatic tissue sterol regulatory element binding protein 2 and low-density lipoprotein receptor in nephrotic syndrome.

@article{Kim2007HepaticTS,
  title={Hepatic tissue sterol regulatory element binding protein 2 and low-density lipoprotein receptor in nephrotic syndrome.},
  author={Choong Hun Kim and Hyun Jin Kim and Masato Mitsuhashi and Nosratola D. Vaziri},
  journal={Metabolism: clinical and experimental},
  year={2007},
  volume={56 10},
  pages={1377-82}
}
Hypercholesterolemia is a main feature of nephrotic syndrome (NS) and is, in part, caused by acquired low-density lipoprotein (LDL) receptor deficiency. The LDL receptor deficiency in NS is accompanied by normal hepatic LDL receptor messenger RNA (mRNA) abundance. Expression of LDL receptor, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, and… CONTINUE READING