Hepatic stellate cells support hematopoiesis and are liver-resident mesenchymal stem cells.

@article{Kordes2013HepaticSC,
  title={Hepatic stellate cells support hematopoiesis and are liver-resident mesenchymal stem cells.},
  author={Claus Kordes and Iris Sawitza and Silke G{\"o}tze and Dieter H{\"a}ussinger},
  journal={Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology},
  year={2013},
  volume={31 2-3},
  pages={290-304}
}
BACKGROUND/AIMS Hematopoiesis can occur in the liver, when the bone marrow fails to provide an adequate environment for hematopoietic stem cells. Hepatic stellate cells possess characteristics of stem/progenitor cells, but their contribution to hematopoiesis is not known thus far. METHODS Isolated hepatic stellate cells from rats were characterized with respect to molecular markers of bone marrow mesenchymal stem cells (MSC) and treated with adipocyte or osteocyte differentiation media… CONTINUE READING
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