Hepatic protein kinase C: translocation stimulated by prolactin and partial hepatectomy.

@article{Buckley1987HepaticPK,
  title={Hepatic protein kinase C: translocation stimulated by prolactin and partial hepatectomy.},
  author={Arthur R. Buckley and Charles W. Putnam and Robert Evans and Hugh E. Laird and Gul N. Shah and David W. Montgomery and Diane Haddock Russell},
  journal={Life sciences},
  year={1987},
  volume={41 26},
  pages={
          2827-34
        }
}
Prolactin stimulates a hepatotrophic response similar to that caused by phorbol esters or partial hepatectomy in rats. Since phorbol esters, which activate protein kinase C, mimic prolactin action in liver, the relationship between prolactin administration and subsequent hepatic protein kinase C translocation was assessed. Prolactin administration rapidly stimulated a 4-fold elevation of membrane protein kinase C activity. The effect of prolactin on hepatic protein kinase C was specific for… CONTINUE READING

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