Hepatic preconditioning in rats is defined by a balance of adenosine and xanthine.

@article{Peralta1998HepaticPI,
  title={Hepatic preconditioning in rats is defined by a balance of adenosine and xanthine.},
  author={Carmen Peralta and Daniel Closa and Carme Xaus and Emilio Gelp{\'i} and Joan Rosell{\'o}-Catafau and Georgina Hotter},
  journal={Hepatology},
  year={1998},
  volume={28 3},
  pages={768-73}
}
The present work investigates the relationship between adenosine, nitric oxide (NO), and free radicals during ischemic preconditioning in rat liver. For this purpose, we evaluated: 1) the efficacy of different periods of preconditioning; 2) the changes in the concentration of adenine nucleotides during preconditioning; 3) the importance of adenosine and xanthine concentrations in the induction of preconditioning; and 4) the possible effect of xanthine oxidase-derived superoxide anion on NO… CONTINUE READING

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