Hepatic phosphatidylethanolamine methyltransferase activity is decreased by ethanol and increased by phosphatidylcholine.

@article{Lieber1994HepaticPM,
  title={Hepatic phosphatidylethanolamine methyltransferase activity is decreased by ethanol and increased by phosphatidylcholine.},
  author={Charles S. Lieber and Sander J. Robins and Maria Anna Leo},
  journal={Alcoholism, clinical and experimental research},
  year={1994},
  volume={18 3},
  pages={592-5}
}
UNLABELLED Phosphatidylethanolamine N-methyltransferase participates in the synthesis of membrane phosphatidylcholine. Its activity was reported to be decreased in patients with alcoholic cirrhosis, but it is not known whether this is a consequence of the cirrhosis or precedes it. This question was studied in a baboon model of alcohol-induced fibrosis. Phosphatidylethanolamine N-methyltransferase activity was measured in sequential percutaneous needle liver biopsies by the conversion of… CONTINUE READING

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