Hepatic microcirculation in fatty liver disease.

@article{Farrell2008HepaticMI,
  title={Hepatic microcirculation in fatty liver disease.},
  author={Geoffrey C. Farrell and Narcissus C.‐H. Teoh and Robert S. McCuskey},
  journal={Anatomical record},
  year={2008},
  volume={291 6},
  pages={684-92}
}
Nonalcoholic fatty liver disease (NAFLD), the most common cause of steatosis, is associated with visceral obesity and insulin resistance. With more severe risk factors (obesity, type 2 diabetes [T2D], metabolic syndrome), steatosis may be complicated by hepatocellular injury and liver inflammation (steatohepatitis or NASH). NASH can lead to perisinusoidal fibrosis and cirrhosis. Fat-laden hepatocytes are swollen, and in steatohepatitis, further swelling occurs due to hydropic change (ballooning… CONTINUE READING
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Effect of extended cold ischaemia with UW solution on graft function after liver transplantation

  • R Adam, H Bismuth, +4 authors D Castaing
  • Lancet
  • 1992
Highly Influential
4 Excerpts

The natural history of nonalcoholic fatty liver disease : a population - based cohort study

  • LA Adams, JF Lymp, J StSauver, SO Sanderson, KD Lindor, P Angulo
  • Gastroenterology
  • 2005
Highly Influential
14 Excerpts

Role of endotoxin in the hepatic microvascular inflammmatory response to ethanol

  • RS McCuskey, Y Ito, GR Robertson, M Perry, GC Farrell
  • J Gastroenterol Hepatol
  • 1995
Highly Influential
4 Excerpts

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