Hepatic metallothionein in a teleost (Prochilodus scrofa) exposed to copper at pH 4.5 and pH 8.0.

@article{Carvalho2004HepaticMI,
  title={Hepatic metallothionein in a teleost (Prochilodus scrofa) exposed to copper at pH 4.5 and pH 8.0.},
  author={Cleoni dos Santos Carvalho and Helo{\'i}sa Sobreiro Selistre de Ara{\'u}jo and Marisa Narciso Fernandes},
  journal={Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology},
  year={2004},
  volume={137 2},
  pages={
          225-34
        }
}
Copper accumulation and induction of metallothionein (MT) were investigated in the liver of juvenile Prochilodus scrofa exposed to copper (96 h-LC50) at pH 4.5 (LC50=98+/-0.8 microg Cu l(-1)) and pH 8.0 (LC50=16+/-0.5 microg Cu l(-1)) at 20 degrees C. No significant difference was found in copper accumulated in the liver at either pH. The ratio between copper accumulation in the liver after 96 h exposure and the copper in the water at pH 4.5 and 8.0 was 5.1 and 34.4, respectively. MT in the… CONTINUE READING
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