Hepatic lipase activity is lower in African American men than in white American men: effects of 5' flanking polymorphism in the hepatic lipase gene (LIPC).

@article{Vega1998HepaticLA,
  title={Hepatic lipase activity is lower in African American men than in white American men: effects of 5' flanking polymorphism in the hepatic lipase gene (LIPC).},
  author={Gloria Lena Vega and Luther T. Clark and Armando Tang and Santica S Marcovina and Scott M Grundy and Jonathan C. Cohen},
  journal={Journal of lipid research},
  year={1998},
  volume={39 1},
  pages={228-32}
}
Plasma high density lipoprotein cholesterol (HDL-C) concentrations are higher in African American men than in white men, but the mechanism(s) responsible for this ethnic difference has not been elucidated. This study examined the relationship between hepatic lipase activity, plasma HDL-C concentrations, and a hepatic lipase polymorphism (-514T) in African American and white American men. Consistent with previous reports, plasma HDL-C concentrations were significantly higher in African American… CONTINUE READING