Hepatic ischaemia-reperfusion injury from bench to bedside.

@article{Bahde2010HepaticII,
  title={Hepatic ischaemia-reperfusion injury from bench to bedside.},
  author={Ralf Bahde and H U Spiegel},
  journal={The British journal of surgery},
  year={2010},
  volume={97 10},
  pages={1461-75}
}
BACKGROUND Vascular occlusion to prevent haemorrhage during liver resection causes ischaemia-reperfusion (IR) injury. Insights into the mechanisms of IR injury gathered from experimental models have contributed to the development of therapeutic approaches, some of which have already been tested in randomized clinical trials. METHODS The review was based on a PubMed search using the terms 'ischemia AND hepatectomy', 'ischemia AND liver', 'hepatectomy AND drug treatment', 'liver AND… CONTINUE READING

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