Hepatic iron metabolism gene expression profiles in HFE associated hereditary hemochromatosis.

Abstract

BACKGROUND Individuals with pathogenic mutations in HFE, hemojuvelin (HJV) and transferrin receptor 2 (TfR2) have low levels of hepcidin, but little is known about the hepatic expression of these molecules in patients with physiological iron overload or HFE associated Hemochromatosis (HH). AIMS To examine the hepatic mRNA expression of iron homeostasis… (More)

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@article{Gleeson2007HepaticIM, title={Hepatic iron metabolism gene expression profiles in HFE associated hereditary hemochromatosis.}, author={Ferga Gleeson and Eleanor Ryan and Sharon Barrett and Jennifer Lin Russell and John Phil Crowe}, journal={Blood cells, molecules & diseases}, year={2007}, volume={38 1}, pages={37-44} }