Hepatic iron concentration and total body iron stores in thalassemia major.

@article{Angelucci2000HepaticIC,
  title={Hepatic iron concentration and total body iron stores in thalassemia major.},
  author={Emanuele Angelucci and Gary M. Brittenham and Christine E. McLaren and Marta Ripalti and Donatella Baronciani and Claudio Giardini and M. C. Galimberti and Paola Polchi and G. Lucarelli},
  journal={The New England journal of medicine},
  year={2000},
  volume={343 5},
  pages={327-31}
}
BACKGROUND AND METHODS We tested the usefulness of measuring the hepatic iron concentration to evaluate total body iron stores in patients who had been cured of thalassemia major by bone marrow transplantation and who were undergoing phlebotomy treatment to remove excess iron. RESULTS We began treatment with phlebotomy a mean (+/-SD) of 4.3+/-2.7 years after transplantation in 48 patients without hepatic cirrhosis. In the group of 25 patients with liver-biopsy samples that were at least 1.0… CONTINUE READING

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