Hepatic injury associated with diphenylhydantoin therapy. A clinicopathologic study of 20 cases.

Abstract

Although the toxicity of diphenylhydantoin in a number of target organs is discussed in numberous reports, hepatotoxic reactions are quite rare. The hepatic lesion has mostly been described as necrosis or hepatitis. Tissue sections from 20 patients who had validated diphenylhydantoin hepatotoxicity were reviewed to define this entity. The morphologic… (More)

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@article{Mullick1980HepaticIA, title={Hepatic injury associated with diphenylhydantoin therapy. A clinicopathologic study of 20 cases.}, author={F G Mullick and Karim Ishak}, journal={American journal of clinical pathology}, year={1980}, volume={74 4}, pages={442-52} }