Hepatic injury after whole-liver irradiation in the rat.


Radiation-induced hepatic injury in rats, which is characterized by marked ascites accompanied by liver necrosis, fibrosis, and vein lesions, is described in this study. These adverse sequelae are produced within 30 days after irradiation if there is surgical removal of two-thirds of the liver immediately after whole-liver irradiation. The LD50/30 day and… (More)


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@article{Geraci1985HepaticIA, title={Hepatic injury after whole-liver irradiation in the rat.}, author={Julia Geraci and K. L. Jackson and Miriam Mariano and Jaina Leitch}, journal={Radiation research}, year={1985}, volume={101 3}, pages={508-18} }