Hepatic injury, liver monitoring and the beta-interferons for multiple sclerosis

  title={Hepatic injury, liver monitoring and the beta-interferons for multiple sclerosis},
  author={H. Tremlett and J. Oger},
  journal={Journal of Neurology},
  • H. Tremlett, J. Oger
  • Published 2004
  • Medicine
  • Journal of Neurology
  • This review explores the salient issues surrounding liver injury and liver monitoring associated with beta-interferon (IFNB) treatment for multiple sclerosis (MS). Post-marketing studies have found a higher proportion of IFNB-treated MS patients with elevated aminotransferases than reported in the pivotal clinical trials. Although the risk of severe liver injury appears small, the true incidence is unknown. Post-marketing studies have shown that the greatest period of risk for the development… CONTINUE READING
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