Hepatic injury, liver monitoring and the beta-interferons for multiple sclerosis
@article{Tremlett2004HepaticIL, title={Hepatic injury, liver monitoring and the beta-interferons for multiple sclerosis}, author={H. Tremlett and J. Oger}, journal={Journal of Neurology}, year={2004}, volume={251}, pages={1297-1303} }
This review explores the salient issues surrounding liver injury and liver monitoring associated with beta-interferon (IFNB) treatment for multiple sclerosis (MS). Post-marketing studies have found a higher proportion of IFNB-treated MS patients with elevated aminotransferases than reported in the pivotal clinical trials. Although the risk of severe liver injury appears small, the true incidence is unknown. Post-marketing studies have shown that the greatest period of risk for the development… CONTINUE READING
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References
SHOWING 1-10 OF 72 REFERENCES
Fulminant liver failure during interferon beta treatment of multiple sclerosis
- Medicine
- Neurology
- 2001
- 58
- PDF
Hepatic reactions during treatment of multiple sclerosis with interferon-beta-1a: incidence and clinical significance.
- Medicine
- Drug safety
- 2003
- 49
Serum transaminase elevations as indicators of hepatic injury following the administration of drugs.
- Medicine
- Regulatory toxicology and pharmacology : RTP
- 1998
- 191
- PDF
Possible mechanisms of elevation of serum transaminase levels during interferon-β therapy in chronic hepatitis C patients
- Medicine
- Journal of Gastroenterology
- 2002
- 11
Liver injury associated with the &bgr;-interferons for MS: A comparison between the three products
- Medicine
- Neurology
- 2004
- 73
- PDF
Liver and thyroid function and autoimmunity during interferon-β1b treatment for MS
- Medicine
- Neurology
- 2001
- 51
Canadian Association of Gastroenterology Practice Guidelines: evaluation of abnormal liver enzyme tests.
- Medicine
- Canadian journal of gastroenterology = Journal canadien de gastroenterologie
- 1998
- 30
- PDF