• DOI:10.1007/s00415-004-0619-5
Corpus ID: 12529733

Hepatic injury, liver monitoring and the beta-interferons for multiple sclerosis

@article{Tremlett2004HepaticIL,
  title={Hepatic injury, liver monitoring and the beta-interferons for multiple sclerosis},
  author={H. Tremlett and J. Oger},
  journal={Journal of Neurology},
  year={2004},
  volume={251},
  pages={1297-1303}
}

H. Tremlett, J. Oger

Published 2004

Medicine

Journal of Neurology

This review explores the salient issues surrounding liver injury and liver monitoring associated with beta-interferon (IFNB) treatment for multiple sclerosis (MS). Post-marketing studies have found a higher proportion of IFNB-treated MS patients with elevated aminotransferases than reported in the pivotal clinical trials. Although the risk of severe liver injury appears small, the true incidence is unknown. Post-marketing studies have shown that the greatest period of risk for the development… CONTINUE READING

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