Hepatic imaging with iodinated nanoparticles: a comparison with iohexol in rabbits.


RATIONALE AND OBJECTIVES We evaluated the efficacy of a particulate computed tomography (CT) contrast agent in an animal model of focal liver disease. METHODS Ethyl ester of diatrizoic acid (EEDA) is an iodinated (89 mg I/ml) nanoparticulate (200 nm) contrast agent intended for intravenous use that is currently undergoing preclinical testing in our… (More)