Hepatic drug transporters, old and new: pharmacogenomics, drug response, and clinical relevance.

Abstract

Interindividual variation in drug response continues to pose a considerable challenge to optimal drug therapy. Drug-metabolizing enzymes have been established as critical determinants of drug disposition and response, and drug transporters are becoming widely appreciated for their role in these processes. We now know that transport is required for many… (More)
DOI: 10.1002/hep.23233

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