Hepatic differentiation capability of rat bone marrow-derived mesenchymal stem cells and hematopoietic stem cells.

@article{Shu2004HepaticDC,
  title={Hepatic differentiation capability of rat bone marrow-derived mesenchymal stem cells and hematopoietic stem cells.},
  author={Sai-nan Shu and Lai Wei and Jiang-hua Wang and Yu-Tao Zhan and Hong-song Chen and Yu Wang},
  journal={World journal of gastroenterology},
  year={2004},
  volume={10 19},
  pages={
          2818-22
        }
}
AIM To investigate the different effects of mesenchymal stem cells (MSCs) and hematopoietic stem cells (HSCs) on hepatic differentiation. METHODS MSCs from rat bone marrow were isolated and cultured by standard methods. HSCs from rat bone marrow were isolated and purified by magnetic activated cell sorting. Both cell subsets were induced. Morphology, RT-PCR and immunocytochemistry were used to identify the hepatic differentiation grade. RESULTS MSCs exhibited round in shape after… CONTINUE READING

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