Hepatic changes in the failing Fontan circulation.

  title={Hepatic changes in the failing Fontan circulation.},
  author={Christoph H Kiesewetter and Nick Sheron and Joseph J Vettukattill and Nigel Hacking and Brian Stedman and Harry Millward-Sadler and Marcus Haw and Richard Cope and Anthony P. Salmon and Muthukumaran C. Sivaprakasam and Tim Kendall and Barry R. Keeton and John Peter Iredale and Gruschen R. Veldtman},
  volume={93 5},
BACKGROUND The failing Fontan circulation is associated with hepatic impairment. The nature of this liver injury is poorly defined. OBJECTIVE To establish the gross and histological liver changes of patients with Fontan circulation relative to clinical, biochemical and haemodynamic findings. METHODS Patients were retrospectively assessed for extracardiac Fontan conversion between September 2003 and June 2005, according to an established clinical protocol. Twelve patients, mean age 24.6… CONTINUE READING
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