Hepatic biotransformation and choleretic effect of 7-ketolithocholic acid in the rat

@article{Kanai1989HepaticBA,
  title={Hepatic biotransformation and choleretic effect of 7-ketolithocholic acid in the rat},
  author={Setsuko Kanai and Yuko Sato and Munetaka Nokubo and Kenichi Kitani},
  journal={Lipids},
  year={1989},
  volume={24},
  pages={859-865}
}
Hepatic biotransformation and the effect on bile flow of 7-ketolithocholic acid (7-oxo-3α-hydroxy-5β-cholan-24-oic acid), in comparison to ursodeoxycholic acid, were examined in rats under conditions of continuous infusion of solutions of sodium salts of these bile acids (1.2μmol/min/100 g body wt) for 2 hr. Both bile salts elevated the bile flow rate as… CONTINUE READING