Hepatic arterial infusion with oxaliplatin, folinic acid, and 5-fluorouracil in patients with hepatic metastases from colorectal cancer: role of carcino-embryonic antigen in assessment of response.

@article{Kern2000HepaticAI,
  title={Hepatic arterial infusion with oxaliplatin, folinic acid, and 5-fluorouracil in patients with hepatic metastases from colorectal cancer: role of carcino-embryonic antigen in assessment of response.},
  author={Wolfgang Kern and Bertrand Beckert and Norbert Lang and Tobias Waggershauser and Jan Braess and Andreas Schalhorn and Wolfgang Hiddemann},
  journal={Anticancer research},
  year={2000},
  volume={20 6D},
  pages={4973-5}
}
BACKGROUND Therapy for patients with hepatic metastases from colorectal cancer (CRC) remains controversial and may be improved by regional oxaliplatin which proved to be effective when administered systemically to patients with advanced CRC. METHODS During the current study, which aims to determine the maximum tolerated dose, the dose-limiting toxicity, and the pharmacokinetics of oxaliplatin applied as hepatic intra-arterial infusion combined with folinic acid and 5-fluorouracil in patients… CONTINUE READING