Hepatic and splenic stiffness augmentation assessed with MR elastography in an in vivo porcine portal hypertension model.

@article{Yin2013HepaticAS,
  title={Hepatic and splenic stiffness augmentation assessed with MR elastography in an in vivo porcine portal hypertension model.},
  author={Meng Yin and Arunark Kolipaka and David A. Woodrum and Kevin J. Glaser and Anthony J. Romano and Armando Manduca and Jayant Talwalkar and Philip A Araoz and Kiaran P. McGee and Nandan S. Anavekar and Richard L. Ehman},
  journal={Journal of magnetic resonance imaging : JMRI},
  year={2013},
  volume={38 4},
  pages={809-15}
}
PURPOSE To investigate the influence of portal pressure on the shear stiffness of the liver and spleen in a well-controlled in vivo porcine model with magnetic resonance elastography (MRE). A significant correlation between portal pressure and tissue stiffness could be used to noninvasively assess increased portal venous pressure (portal hypertension), which is a frequent clinical condition caused by cirrhosis of the liver and is responsible for the development of many lethal complications… CONTINUE READING

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