Hepatic Gene Expression Profiles Differentiate Steatotic and Non-steatotic Grafts in Liver Transplant Recipients

@inproceedings{eda2019HepaticGE,
  title={Hepatic Gene Expression Profiles Differentiate Steatotic and Non-steatotic Grafts in Liver Transplant Recipients},
  author={Ondřej {\vS}eda and Monika Cahova and Irena M{\'i}kov{\'a} and Lucie {\vS}edov{\'a} and Helena Daňkov{\'a} and Marie Heczkov{\'a} and Miriam Bratova and Nikola Ď{\'a}skov{\'a} and Denisa Erhartova and V{\'a}clav {\vC}apek and Blanka Chyl{\'i}kov{\'a} and Pavel Trune{\vc}ka},
  booktitle={Front. Endocrinol.},
  year={2019}
}
Background: Liver transplantation leads to non-alcoholic fatty liver disease or non-alcoholic steatohepatitis in up to 40% of graft recipients. The aim of our study was to assess transcriptomic profiles of liver grafts and to contrast the hepatic gene expression between the patients after transplantation with vs. without graft steatosis. Methods: Total RNA was isolated from liver graft biopsies of 91 recipients. Clinical characteristics were compared between steatotic (n = 48) and control (n… CONTINUE READING
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