Hepatic Activity and Transcription of Betaine-Homocysteine Methyltransferase, Methionine Synthase, and Cystathionine Synthase in Periparturient Dairy Cows Are Altered to Different Extents by Supply of Methionine and Choline.

@article{Zhou2017HepaticAA,
  title={Hepatic Activity and Transcription of Betaine-Homocysteine Methyltransferase, Methionine Synthase, and Cystathionine Synthase in Periparturient Dairy Cows Are Altered to Different Extents by Supply of Methionine and Choline.},
  author={Zheng Zhou and Timothy A. Garrow and Xianwen Dong and Daniel N. Luchini and Juan J Loor},
  journal={The Journal of nutrition},
  year={2017},
  volume={147 1},
  pages={11-19}
}
BACKGROUND Compared with choline, Met enhances milk yield and feed intake, and elicits a better immuno-metabolic status in periparturient cows. It is unknown whether hepatic activity and transcription of betaine-homocysteine methyltransferase (BHMT), 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR), and cystathionine β-synthase (CBS) are responsive to Met and choline supply. OBJECTIVE This study sought to characterize hepatic BHMT, MTR, and CBS transcription and activity in… CONTINUE READING
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