Hepatic 31P MRS in rat models of chronic liver disease: assessing the extent and progression of disease.

@article{Corbin2003Hepatic3M,
  title={Hepatic 31P MRS in rat models of chronic liver disease: assessing the extent and progression of disease.},
  author={Ian R. Corbin and Richard Buist and Jim Peeling and Meng Zhang and Julia Uhanova and Gerald Y. Minuk},
  journal={Gut},
  year={2003},
  volume={52 7},
  pages={
          1046-53
        }
}
BACKGROUND Hepatic adenosine triphosphate (ATP) levels are an accurate reflection of functioning hepatic mass following surgical resections and acute liver injury. OBJECTIVE To determine whether hepatic ATP levels can serve as a non-invasive means of documenting progression of chronic liver disease to cirrhosis. METHODS In vivo phosphorus-31 magnetic resonance spectroscopy ((31)P MRS) was performed in three animal models of chronic liver disease. Sixty six adult Sprague- Dawley rats were… CONTINUE READING

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