Hepascore: an accurate validated predictor of liver fibrosis in chronic hepatitis C infection.

@article{Adams2005HepascoreAA,
  title={Hepascore: an accurate validated predictor of liver fibrosis in chronic hepatitis C infection.},
  author={Leon Anton Adams and Max Kishor Bulsara and Enrico Rossi and Bastiaan Deboer and David Speers and Jacob George and James G. Kench and Geoffrey Farrell and Geoffrey W Mccaughan and Gary Riley Jeffrey},
  journal={Clinical chemistry},
  year={2005},
  volume={51 10},
  pages={
          1867-73
        }
}
BACKGROUND Staging hepatic fibrosis by liver biopsy guides prognosis and treatment of hepatitis C, but is invasive and expensive. We sought to create an algorithm of serum markers that accurately and reliably predict liver fibrosis stage among hepatitis C patients. METHODS Ten biochemical markers were measured at time of liver biopsy in 117 untreated hepatitis C patients (training set). Multivariate logistic regression and ROC curve analyses were used to create a predictive model for… CONTINUE READING

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