Heparin monitoring during cardiac surgery. Part 2: Calculating the overestimation of heparin by the activated clotting time.

@article{Raymond2003HeparinMD,
  title={Heparin monitoring during cardiac surgery. Part 2: Calculating the overestimation of heparin by the activated clotting time.},
  author={Paul D Raymond and Michael J Ray and Susan Callen and Neville A. Marsh},
  journal={Perfusion},
  year={2003},
  volume={18 5},
  pages={277-81}
}
Activated clotting time (ACT) values were converted to heparin concentration, enabling an assessment of the accuracy of the ACT and a quantification of the prolongation imposed by bypass. Blood samples were obtained from 42 adult cardiopulmonary bypass (CPB) patients before and during bypass surgery. Samples were analysed for ACT (HemoTec ACT) and anti-factor Xa (anti-Xa) plasma heparin concentration. The mean heparin concentration calculated before bypass was an accurate reflection of plasma… CONTINUE READING

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